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Jun 01, 2005 (Vol. 25, No. 11)

PANDORA - Protein ANnotation Diagram ORiented Analysis

  • Uniqueness of idea
  • Mostly for data mining nerds
Open PANDORA's box and you'll find a lot of information. A site with a clever acronym, the second word defining the acronym (Annotation) is the key to understanding this one. In PANDORA, annotations take on a life of their own, serving as a binary property assigned to a protein. With the resources of InterPro, Gene Ontology, ENZYME, and SCOP, among others, at its disposal, PANDORA is able to deliver a tremendous amount of information to the user. PANDORA's approach to analysis is a little hard to describe and rooted in the science of data mining. By examining descriptions and keywords for patterns for individual proteins in each database, PANDORA creates "integrative annotation analysis sets" of protein information. Finally, all of this information is assembled into illustrative diagrams that have to be seen to be undrstood. A very unusual idea, but does it tell anything meaningful?
  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good

*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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