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Oct 15, 2012 (Vol. 32, No. 18)

OligoArchitect

URL:www.oligoarchitect.com
  • Simple design, easy to use
  • Nothing major

Having PCR troubles? Whether you’re running standard PCR applications, qPCR, or even more specialized reactions, one important variable that affects the success (or failure) of the experiment is primer design. There are many online tools to assist with this process, and here is a new player on the primer-design scene: OligoArchitect by Sigma-Aldrich. One advantage that this program has over some others is the fact that it utilizes Premier Biosoft’s Beacon Designer algorithm, an established standard in the field. The website is very bare-boned (but one doesn’t need many bells and whistles for a primer design tool, after all) and simple to use. Users must first complete a free registration to access the tool. After that, they can get to work designing one of five different types of probe: SYBR Green I, Dual-Labeled, Molecular Beacon, Scorpions, or LightCycler probes.

  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good


*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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