Leading the Way in Life Science Technologies

GEN Exclusives

More »

Best of the Web

More »
Feb 15, 2005 (Vol. 25, No. 4)

Merops: The Peptidase Database

  • Well thought out
  • None
You can call them peptidases, proteases, proteinases, or proteolytic enzymes, but whatever you call them, you can probably find them at the Merops database. The site employs an interesting scheme for organizing peptidases. First, they are grouped in families according to statistically significant amino acid sequence similarities, and then families that are thought to be related are placed in clans. One can locate desired peptidases by name or accession number and, in addition, a BLAST function allows one to search the Merops databases with user-supplied sequences. As if that wasn’t enough, the site also contains a database of peptidase inhibitors that can be similarly searched. Another site where the site’s creators have anticipated user needs and designed accordingly.
  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good

*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »