Leading the Way in Life Science Technologies

GEN Exclusives

More »

Best of the Web

More »
October 15, 2012 (Vol. 32, No. 18)

Melina II

  • Nice results display, easy to use
  • Screen shots in help section too small to read

Just as insurance companies boast that they allow shoppers to compare multiple competitors’ rates simultaneously, Melina II is a one-stop online resource for researchers looking to identify potential DNA binding motifs within their sequences of interest. With Melina II, users can analyze their input sequence with up to four promoter analysis programs simultaneously. The five programs from which to choose are: Consensus, MEME, Gibbs sampler, MDscan, and Weeder. Results are displayed in an easy-to-interpret manner, including an alignment that compares the results from each prediction program. In addition to customizable search parameters, Melina II is also equipped with options to either search for the identified consensus sequences in the genome of human, mouse, B. subtilis, or E. coli, or to compare the identified sequence against known transcription factor binding sites.

  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good