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May 01, 2005 (Vol. 25, No. 9)

Human Serum Proteome

  • Good coverage of topic
  • Nothing significant
Proteomes are where it's at for systems biologists. Have you ever wondered how many proteins are known to exist in human serum? I read the last chapter of this "mystery novel" and discovered that 1,444 proteins have been detected. That number, while large, is still surprisingly small to me. At the Human Serum Proteome, one can look at each of the individual protein listings, see pie charts displaying the breakdown of proteins by biological process, cellular component, or molecular function, and search all of the proteins by Swiss-Prot and NCBI identifying numbers. Clicks on hyperlinked protein names brings up gene classification descriptions, Swiss-Prot Accession Numbers, Database Links, and amino acid sequences to identify peptides.
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