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Jun 01, 2011 (Vol. 31, No. 11)

GeneMANIA

URL:genemania.org
  • Advanced search parameters
  • Smaller database than many other comparable tools

This isn’t merely a gene function prediction tool—it’s an agent of gene mania!…Well OK, it’s actually just a gene function prediction tool, but that shouldn’t hinder your enthusiasm for your quest to answer that often-encountered quandary: what the heck does this gene do? The premise is simple: select your model organism of interest (fly, worm, yeast, human, mouse, or Arabidopsis) and enter a list of genes for which you want relationships found. This database may not be the largest out there, but it isn’t too shabby, either. (There are, after all, 185,324,281 interactions included.) One nice aspect of this particular gene interaction prediction tool is the option to select specific types of data or publications to be included in the search. Data types include co-expression studies, co-localizations, genetic interactions, pathways, physical interactions, predictions, and shared protein domains.

  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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