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Despite the fact that 3-D is a hot commodity at the moment—such as for films and television sets—one must remember that lowly 2-D technology serves a great purpose in its own right. Take gel electrophoresis for example. 2-D electrophoresis is a staple technique in proteomics, allowing the separation and characterization of proteins from a heterogeneous sample based on protein charge and molecular mass. The problem with the technology, though, is that fuzzy data spots on the gel can lead to fuzzy interpretation. To combat this, several research groups have developed the “combined correctness metric” to analyze 2-D gels. And, lucky for you, you don’t need to understand exactly how it works in order to take advantage of it, thanks to Ludesi’s free (that’s right—FREE!) Gel IQ application. This application works with your current 2-D gel analysis software (such as ImageMaster, PDQuest, REDFIN, and SameSpots) to determine how correct the analysis is. The Gel IQ website contains the download, as well as additional background information and tutorials.

*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Genetic Engineering & Biotechnology News (GEN) has retained its position as the most widely read biotechnology publication around the globe since its launch in 1981. Published 21 times a year and with additional exclusive editorial content online, GEN's unique news and technology focus includes the entire bioproduct life cycle from early-stage R&D, to applied research including omics, biomarkers, as well as diagnostics, to bioprocessing and commercialization.

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