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Jun 15, 2010 (Vol. 30, No. 12)

Gel IQ

URL:www.ludesi.com/free-tools/geliq
  • Nice background information regarding the application
  • Nothing major

Despite the fact that 3-D is a hot commodity at the moment—such as for films and television sets—one must remember that lowly 2-D technology serves a great purpose in its own right. Take gel electrophoresis for example. 2-D electrophoresis is a staple technique in proteomics, allowing the separation and characterization of proteins from a heterogeneous sample based on protein charge and molecular mass. The problem with the technology, though, is that fuzzy data spots on the gel can lead to fuzzy interpretation. To combat this, several research groups have developed the “combined correctness metric” to analyze 2-D gels. And, lucky for you, you don’t need to understand exactly how it works in order to take advantage of it, thanks to Ludesi’s free (that’s right—FREE!) Gel IQ application. This application works with your current 2-D gel analysis software (such as ImageMaster, PDQuest, REDFIN, and SameSpots) to determine how correct the analysis is. The Gel IQ website contains the download, as well as additional background information and tutorials.

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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