Advances in PCR Technology and Its Applications in Healthcare Research
Breaking Through Barriers between Benchtop and Bedside
Cannibalism: A Biological and Evolutionary Perspective
Sounds of Science Podcast
Ubiquitin System: The Next Class of Drug Targets?
A Complex Role in Cellular Process & Growing Tool Set to Elucidate It
Bispecific Antibodies Close in on Cancer
Plotting Molecular Pincer Movements, Denying Cancer Room to Maneuver
So which came first, the chicken or the egg…nog? While this enigma may continue to plague humanity, at least there are a number of evolution-related questions that are more answerable. For instance, how have ancestral genes evolved in different species? What do these orthologous genes look like? Enter eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups), which is a database of orthologous groups of genes. Just how many groups, you ask? The database contains a whopping 224,847 groups that cover 630 species. One can either search by gene name or enter up to 30 protein sequences to retrieve the query results. These results include a phylogenetic tree showing the evolution of the protein of interest, as well as brief annotations for the orthologous genes. Also, as a website dedicated to the relationships between genes, the sequence alignment and tree-viewing options are a nice touch.