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May 01, 2010 (Vol. 30, No. 9)


  • Nice introductory page and tutorials, good links
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If you want to explore the complex landscape of gene interactions, Cytoscape makes for an excellent compass. Developed by a consortium funded by the National Institute of General Medical Sciences (NIGMS) of the NIH and the NSF, Cytoscape is an open-source software platform to visualize and analyze complex networks such as biological pathways and molecular interactions. A unique feature of Cytoscape is that it not only allows one to visualize networks, but it also permits the integration of those networks with annotations and other data such as gene-expression profiles. The introduction page provides an excellent overview of Cytoscape’s features including its visualization capabilities, analysis features, and even its multilingual compatibility. In addition to the actual Cytoscape download, the site also gives a number of links to other software downloads, data-exchange formats, and network databases.

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

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