Leading the Way in Life Science Technologies

GEN Exclusives

More »

Best of the Web

More »
May 01, 2005 (Vol. 25, No. 9)

CKAAPs Database

URL:ckaaps.sdsc.edu/perl/browser.pl
  • Powerful analyses
  • Very techie, few descriptions
CPAAP is an acronym for Conserved Key Amino Acid Positions. Analysis of CKAAPs using the database provides help to researchers interested in understanding the relationships between protein sequence and structure. It accomplished this by providing access to analysis of structurally similar proteins, but with dissimilar sequences. Using such a method, key residues within a common fold may be identified. Two different structural alignment algorythms (CE and FSSP)are employed and the analyses are promised to be improved as more and more structures get discovered and refined. This is a site mostly for techies who are into protein structure. If you don't know what the CE and FSSP refer to above, this site probably wont work for you.
  • Key:
  • Strong Points
  • Weak Points
  • Ratings:
  • Excellent
  • Very Good
  • Good


*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

Be sure to take the GEN Poll

Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

More »