Systems Biology Opens New Research Pathways
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Individual Tumor Profiling
Has Tumor Molecular Profiling Enabled More Effective and Less Toxic Cancer Treatment?
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Cancer Genome Anatomy Project
Admittedly, the name of this initiative is a bit…off. (What is a “cancer genome,” anyway? And what is its anatomy like?) But if we forgive the National Cancer Institute for its choice of title, then we can really enjoy the many resources encompassed within the Cancer Genome Anatomy Project (CGAP). With a goal of characterizing the gene-expression profiles of normal, precancer, and cancer cells, the CGAP presents a number of databases and bioinformatics tools to researchers and health professionals through this website. The website is organized around seven themes: genes, tissues, pathways, RNAi, chromosomes, SAGE genie, and tools. Under these headings, visitors will find a “clone finder” database, a link to the shRNA Validation Project, the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (that’s a mouthful!), and FISH-mapped BACs, among other tools.