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Jan 01, 2010 (Vol. 30, No. 1)


  • Variety of search parameters, easy to navigate interface
  • Nothing significant

Just how many ways can you search for enzymes, you ask? Well that is a question to be posed to BRENDA, the “comprehensive enzyme information system” designed by a group at the Technical University of Braunschweig. BRENDA is quite impressive, with over 50 (that’s right, 50!) different search parameters for enzymes. To get an idea, one can search by metabolic pathway, enzyme turnover number, oxidation stability, post-translational modifications, molecular weight, etc. The list goes on and on. The page design is nothing fancy, but beneath the simple interface lies a great deal of information waiting to be unearthed. One need only click to display “all enzymes in BRENDA” to gain an appreciation for the scope of the information. So what are you waiting for? Go catch up on some catalysis!

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*The opinions expressed are solely those of the author(s) and should not be construed as reflecting the viewpoints of the publisher, Genetic Engineering & Biotechnology News, Mary Ann Liebert, Inc., the publishing house, or employees and affiliates thereof.

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Scientifically Studying Ecstasy

MDMA (commonly known as the empathogen “ecstasy”) is classified as a Schedule 1 drug, which is reserved for compounds with no accepted medical use and a high abuse potential. Two researchers from Stanford, however, call for a rigorous scientific exploration of MDMA's effects to identify precisely how the drug works, the data from which could be used to develop therapeutic compounds.

Do you agree that ecstasy should be studied for its potential therapeutic benefits?

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