Presents an Educational and Informative Audio Webinar

Improvements in Amino Acid Analysis for Biotherapeutic Production

 

VIEW ON DEMAND:
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Original Broadcast Date: Monday, December 8, 2008
Duration: 1 hour and 7 minutes

REGISTRATION IS FREE

The analysis of amino acids is required at several stages during the development of biopharmaceutical products. Proteins are hydrolyzed for purposes of identification and as a direct measure of concentration. Free amino acids are indicators of the status of metabolism and are therefore, routinely monitored in optimizing the growth of cell cultures. The need for an accurate and robust amino acid analysis technique is necessary as biotherapeutics become an important class of new pharmaceuticals.

Biopharmaceutical scientists will present real-world examples of routine use of amino acid analysis. This webinar will begin with a background discussion of amino acid analysis including answers to some frequently asked questions. A reliable complete solution for amino acid analysis will be described as it relates to these principles. The incorporation of a new amino acid analysis procedure into cell culture monitoring will be explored in detail. Approaches to non-routine and problematic samples will be explored.

Those who will benefit from attending this webinar include:

  • Biochemists involved in characterization of protein biotherapeutics
  • Process scientists who are optimizing cell culture conditions
  • Pharmaceutical scientists requiring accurate measurement of protein concentration
  • Support chemists who analyze changes in processes and products
  • Stability and QC scientists who monitor changes in protein structure
  • Developers of follow-on biologics

Key learning point for this webinar include:

  • Principles of the development of an amino acid analysis procedure
  • Practical considerations in sample handling and troubleshooting
  • Process of adopting a new amino acids analysis method
  • Analyzing results and handling special samples

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PANELISTS

Kevin Ray, Ph.D.
Manager, Analytical R&D
Sigma-Aldrich

 

Thomas E. Wheat, Ph.D.
Principal Scientist and Life Science Laboratory Manager
Waters

 


MODERATOR

John Sterling
Editor in Chief
Genetic Engineering & Biotechnology News

 

 

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