GEN UPDATES in biotechnology: RNAi

GEN Technology Updates are composed of articles commissioned for publication by Genetic Engineering & Biotechnology News and of peer-reviewed scientific papers from journals published by Mary Ann Liebert, Inc. They are intended to provide in-depth information and coverage on cutting-edge technologies and trends that are transforming drug discovery and life science research.

Recent Developments in the Application of Plasmid DNA-Based Vectors and Small Interfering RNA Therapeutics for Cancer
Martin Meyer, Ernst Wagner

Harnessing RNAi's Gene-Silencing Power
Kathy Liszewski

RNAi-Based Gene Expression Manipulation
Trevor Stokes

Nonviral Approaches to DNA Delivery
Kathy Liszewski

A microRNA component of the p53 tumour suppressor network
Lin He, Xingyue He, Lee P. Lim, Elisa de Stanchina, Zhenyu Xuan, Yu Liang, Wen Xue, Lars Zender, Jill Magnus, Dana Ridzon, Aimee L. Jackson, Peter S. Linsley, Caifu Chen, Scott W. Lowe, Michele A. Cleary, Gregory J. Hannon
Nature 2007 Jun 28;447(7148):1130-4

Tumour suppression - The power of arrest
Arianne Heinrichs
Nature Reviews Molecular Cell Biology 8, 514 - 515 (2007)

Strategies for silencing human disease using RNA interference
Kim DH, Rossi
JJ Nature Review Genetics 2007 Mar;8(3):173-84

Noncoding RNAs and gene silencing
Zaratiegui M, Irvine DV, Martienssen RA
Cell 2007 Feb 23;128(4):763-76.

Perspective: machines for RNAi
Tomari Y, Zamore PD
Genes and Development 2005 Mar 1;19(5):517-29

 

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